Cosmetic Ingredient Review

The Cosmetic Ingredient Review (CIR) Expert Panel is an independent, non-profit scientific body that was established in 1976 to assess the safety of cosmetic ingredients used in the U. S. The expert panel is comprised of world-renowned scientists and physicians who have been publicly nominated by consumer, scientific and medical groups, government agencies and industry. The Personal Care Products Council (the Council) initiated the CIR program at the suggestion and with the support of the Food and Drug Administration (FDA) and the Consumer Federation of America (CFA). FDA, CFA and the Council provide non-voting liaisons to the panel who are actively involved in the comment and discussion process. CIR panel members must meet the same conflict of interest requirements regarding financial interests as special non-government advisory experts to FDA.

For more than 38 years, CIR has examined and evaluated scientific safety data for ingredients used in cosmetics and personal care products in the U.S. and conducts those evaluations in an open, unbiased and expert manner.

CIR develops safety assessment monographs, publishes its work in the peer-reviewed International Journal of Toxicology, and issues an annual comprehensive collection of all CIR reports, including abstracts, discussions and conclusions. Its meetings are held four times a year and are open to the public. Public comments are solicited at each stage of the safety assessment process.

CIR has received several awards, including the American Academy of Dermatology Gold Triangle Award and the National Association of Insurance Agents Consumer Product Safety Award. CIR’s Executive Director, Bart Heldreth, Ph.D., manages all of the staff’s activities to effectively and efficiently implement the program’s procedures.

The CIR website provides additional information about the organization.